Ototoxicity refers to the harmful effects of certain substances, such as medications or chemicals, on the structures of the inner ear and the auditory system. Exposure to ototoxic substances can result in damage to the hair cells of the inner ear, the auditory nerve, or other components involved in the processing of sound signals. This damage can lead to hearing loss, imbalance, or other auditory and vestibular issues. Common ototoxic medications include some antibiotics, certain chemotherapy drugs, loop diuretics, and nonsteroidal anti-inflammatory drugs (NSAIDs). Individuals taking medications with ototoxic potential should be monitored closely by healthcare professionals, and the benefits of the medication should be weighed against the potential risks to hearing health. Regular hearing check-ups are particularly important for those exposed to ototoxic substances to detect any changes in hearing early on.